Caffeine 10% – Lipolytic Solution
Not for injection. For topical use only: via microneedling (Dermapen, derma roller) or non-invasive transdermal delivery systems.
Mechanism of Action
•    Stimulation of metabolism
•    Reduction in the size of fat cells
•    Elimination of excess fluid and salts (via urine)
•    Skin tightening and reduction in the visible appearance of cellulite
Indications
•    Cellulite
•    Under-eye area: puffiness and dark circles
•    Localized fat deposits
•    Hair loss
Application: Microneedling or non-invasive transdermal delivery system
Dosage: One session, one area — one full 2 ​​ml ampoule; apply to clean, damp skin.

Under-eye Area
Action: Caffeine constricts subcutaneous blood vessels and promotes drainage. The effect is rapid but temporary; therefore, a full course of treatment is required.
Patient Profile: Morning puffiness; vascular-type dark circles.
Technique:
•    The mobile eyelid and the tear trough area should be avoided. •    Needle depth: General guideline for the face is 0.25–1.0 mm; for the eye area, 0.25 mm.

Contraindications and Precautions
•    Inflamed, infected, or damaged skin in the treatment area.
•    Individual hypersensitivity or allergy to any of the components.
•    Adherence to aseptic and antiseptic standards is mandatory.
•    Written informed consent from the patient is required prior to the procedure.
•    Expected reaction: Redness following microneedling